Bupivacaine Liposomal versus Bupivacaine: Comparative Review
نویسندگان
چکیده
منابع مشابه
Liposomal bupivacaine: a review of a new bupivacaine formulation
Many attempts have been made to increase the duration of local anesthetic action. One avenue of investigation has focused on encapsulating local anesthetics within carrier molecules to increase their residence time at the site of action. This article aims to review the literature surrounding the recently approved formulation of bupivacaine, which consists of bupivacaine loaded in multivesicular...
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BACKGROUND In the past, the efficacy of local infiltration of liposomal bupivacaine for total hip arthroplasty (THA) patients was in debate. Therefore, this meta-analysis was conducted to determine whether local infiltration of liposomal bupivacaine provides better pain relief after THA. METHODS We searched Web of Science, PubMed, Embase, and the Cochrane Library databases to the April 2017. ...
متن کاملTreatment of Digital Ischemia with Liposomal Bupivacaine
Objective. This report describes a case in which the off-label use of liposomal bupivacaine (Exparel) in a peripheral nerve block resulted in marked improvement of a patient's vasoocclusive symptoms. The vasodilating and analgesic properties of liposomal bupivacaine in patients with ischemic symptoms are unknown, but our clinical experience suggests a role in the management of patients sufferin...
متن کاملLiposomal extended-release bupivacaine for postsurgical analgesia
When physicians consider which analgesia to use postsurgery, the primary goal is to relieve pain with minimal adverse side effects. Bupivacaine, a commonly used analgesic, has been formulated into an aqueous suspension of multivesicular liposomes that provide long-lasting analgesia for up to 72 hours, while avoiding the adverse side effects of opioids. The increased efficacy of liposomal extend...
متن کاملLiposomal Bupivacaine in Implant-Based Breast Reconstruction
Purpose This study evaluates the role of liposomal bupivacaine in implant-based breast reconstruction. Methods A prospective, randomized, single-blind trial of liposomal bupivacaine in implant-based breast reconstruction was performed. Patients in the control arm were treated with 20 mL 0.25% bupivacaine with epinephrine 1:200,000 to each breast pocket. Patients in the experimental arm were t...
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ژورنال
عنوان ژورنال: Hospital Pharmacy
سال: 2014
ISSN: 0018-5787,1945-1253
DOI: 10.1310/hpj4906-539